C. Michael Gibson, M.D.

C. Michael Gibson, M.S., M.D. is an interventional cardiologist, cardiovascular researcher and educator who pioneered our understanding of the "open artery hypothesis" as well our understanding of the importance of restoring flow downstream in the capillary bed in the "open microvasculature hypothesis" in heart attack. Gibson has been a leading investigator in trials of thrombolytic agents, glycoprotein 2b3a inhibitor agents, thienopyridines, factor Xa inhibitors, lipid lowering agents and new devices. Gibson was named one of the world's most widely published and cited scientists of past decade in 2014 by Thomson Reuters.

Gibson founded and led his own Academic Research Organization (PERFUSE) for 30 years, & has been principal investigator of or led core services for >120 clinical trials, the results of which have been published in leading journals. Under Gibson's direction, PERFUSE created the master database that unified data from over many years of TIMI studies (TIMI 1-50) in nearly 100,000 patients and coordinated data analyses for the TIMI study group and functioned as the TIMI Data Coordinating Center. Gibson has led phase 1-4 clinical trials, and cardiology megatrials of over 15,000 patients which eventuate in international approval of drugs like prasugrel, rivaroxaban and betrixaban.

Gibson also founded www.wikidoc.org and www.wikipatient.org , widely viewed open source textbooks of medicine. He is Editor-In-Chief of >2,200 active contributors who have edited the content millions of times. Gibson also founded www.clinicaltrialresults.org and has conducted >2,000 TV / video interviews. He has over 340K followers on twitter with millions of impressions at major meetings.

For years, Gibson has been chosen as one of Boston's Top Doctors & U.S. News & World Report also lists Gibson as one of America's top doctors. He has held numerous leadership positions in medicine including positions as a Coronary Care Unit Director, a Cardiac Catheterization Laboratory Director, a Chief of Cardiology and as a Vice Chairman of Medicine.

Disclosures

Dr. Gibson follows the conflict of interest policies set forth by Harvard Medical School and the Beth Israel Deaconess Medical Center. The Baim Institute follows the same conflict of interest policies as Harvard Medical School and Beth Israel Deaconess Medical Center. The dates of payments are based on the date payment was received (on a cash basis) rather than the date of billing (accrual basis).

Executive Position (with $0.00 monies received by Dr. Gibson)

Chief Executive Office, Baim Institute for Clinical Research

Present Research/Grant Funding (within the last year)

Ongoing: Angel Medical Corporation; Bayer Corp.; CSL Behring; Janssen Pharmaceuticals; Johnson & Johnson Corporation; SCAD Alliance;

Terminated but within one year: Portola Pharmaceuticals (contract terminated with BIDMC on 12/31/2017)

Consulting

Amarin Pharama, Amgen, Bayer Corporation, Boehringer Ingelheim, Boston Clinical Research Institute, Cardiovascular Research Foundation, Chiesi, CSL Behring, Eli Lilly, Gilead Sciences, Inc., Impact Bio LTD, Janssen Pharmaceuticals, Johnson & Johnson Corporation, The Medicines Company, MedImmune, Medtelligence, Merck & Co, Inc., The Medicine’s Company, Microport, Novo Nordisk, Pharma Mar, Portola Pharmaceuticals (began 1/1/2018), Sanofi, Somahlution, Verseon Corportation, Web MD

For Trials that Dr. Gibson actively serves as PI of and receives research grant support on an ongoing basis, there is less than $25,000 per year in consulting monies received per the Harvard, BIDMC, Baim policies.

Equity

nference

Royalties as a Contributor

UpToDate in Cardiovascular Medicine

Spouse conflicts of interests (Employee of Boston Clinical Research Institute)

Amarin, Amgen, Bayer, Boehringer Ingelheim, Boston Scientific, Cardiovascular Research Foundation, Chiesi, Eli Lilly, Gilead Sciences, Inc., Impact Bio, Janssen, Johnson and Johnson, The Medicines Company, Medtelligence, MedImmune, Merck & Co. Inc., Novo Nordisk, PharmaMar, Portola, Sanofi, Somahlution, Verseon Corporation