Dr. Darren McGuire is a general cardiologist and clinical trialist with expertise in large-scale CV outcomes trial design and execution, and drug registration/regulation, with a focus on diabetes and cardiovascular disease. He has had leadership roles for numerous international cardiovascular clinical outcomes trials, including T2DM, obesity, and lipid trials. Dr. McGuire is a previous member of the FDA Cardiovascular and Renal Drugs Advisory Committee and remains an FDA ad hoc consultant. He is Deputy Editor of Circulation, Senior Editor of Diabetes and Vascular Disease Research, co-editor of the textbook: Diabetes in Cardiovascular Disease: A Companion to Braunwald’s Heart Disease and Chair of the AHA Diabetes Committee. Dr. McGuire has authored/co-authored over 450 peer-reviewed manuscripts, reviews, editorials and book chapters and from 2021-present, he has been recognized as a Clarivate Highly Cited Researcher.